Bill and Melinda Gates say they are going their separate ways after 27 years of being married.
They first met in the 1980s when Melinda joined Bill’s Microsoft firm.
The billionaire couple have three children and jointly run the Bill & Melinda Gates Foundation.
The Gates along with investor Warren Buffett are behind the Giving Pledge, which calls on billionaires to commit to giving away the majority of their wealth to good causes.
Bill Gates is the fourth wealthiest person in the world, according to Forbes, and is worth $124bn (£89bn).
The organisation has spent billions fighting causes such as infectious diseases and encouraging vaccination of children.