Portugal, winners of the inaugural Nations League, shrugged off the absence of Ronaldo because of a positive COVID-19 test as they beat Sweden 3-0 in Lisbon.
Liverpool’s Diogo Jota set up Bernardo Silva for the opener then scored two of his own, one either side of half-time.
Meanwhile, the prolific Robert Lewandowski scored a brace as Poland beat Bosnia and Herzegovina 3-0 in Warsaw.
Karol Linetty got the other goal and Poland are top of Group A, a point above Italy and two ahead of the Netherlands.
The Dutch came from behind to draw 1-1 with Italy in Bergamo, with Donny van de Beek netting for Frank de Boer’s side after Lorenzo Pellegrini put Italy ahead.